10 January 2009

Real-time DNA Sequencing

A paper in Science (Real-Time DNA Sequencing from Single Polymerase Molecules) has reported a new technique that can sequence DNA 30,000 times faster than current techniques. The researchers are using tiny hollow metal cylinders (ZMW waveguides) on a chip to isolate single molecules of DNA and visualise the flourescing nucleotides as they are incorporated into DNA chains. There is a quicktime movie of this happening and a podcast interview with the researchers. The possibility of being able to sequence an entire human genome in under half an hour to 99.999% accuracy for under $1000 has become very real (at least this is what the biotech company conducting the research hopes).

The impact on bioinformatic research would be huge.

 

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About david.glance

A technologist, working at UWA with students and other staff to research, develop and educate in the areas of web software and design.

UWA Centre for Software Practice in 2006 and have been developing software for universities and in the e-Health market.